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Treflan / trifluralin

Chemical Structure

Chemical Name:

2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl) benzenamine.

Chemical Family:


WSSA Resistance Group:


Crop/non-crop registration:

Soybeans, beans, canola, direct-seeded alfalfa, transplants of tomatoes, peppers, cole crops, carrots, strawberries

Sensitive weeds:

Annual grasses; will provide good control of pigweed and lambsquarters including triazine-resistant biotypes.

Application method:

PPI - incorporate to 8-10 cm (3"-4"); should be incorporated within 24 hrs to avoid volatilization and photodegradation losses, especially on moist soils.

Absorption & Translocation:

Readily absorbed by young roots and shoots but no significant translocation;susceptible weeds are controlled as they germinate (affects shoots: grass coleoptile, BLW (broadleaf weeds): hypocotyl/epicotyl). Established weeds are not controlled.

Mode of Action:

Disruption of mitosis (inhibitor of microtubule synthesis).

Metabolic pathway inhibited:

Binds to tubulin, the major microtubule protein; leads to microtubule loss and absence of spindle apparatus. This prevents the alignment and separation of chromosomes during mitosis. Dinitroaniline-induced microtubule loss typically results in the swelling of root tips as cells in this region fail to divide or elongate.

Basis of Selectivity:

Physiological growth processes associated with seed germination.


Inhibits root and shoot growth; initial effects observed on roots, especially the development of lateral or secondary roots; leads to thickened and stubby primary roots, especially tips. Inhibition of shoot growth is a secondary effect caused by limited root growth. Most weeds affected do not emerge from soil, but if they do, typically have one or two leaves.


Intermediate (1-4 months); recommended rates provide season long control.


Oral LD50 >5000 mg/kg - practically non-toxic.

Additional comments:

Strongly adsorbed to soil particles with negligible leaching; soil organic matter and clay content thus affect application rates; activated upon incorporation; rainfall is not required.